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Hairless-binding deficient Suppressor of Hairless alleles reveal Su(H) protein levels are dependent on complex formation with Hairless.

Cell fate choices during metazoan development are driven by the highly conserved Notch signalling pathway. Notch receptor activation results in release of the Notch intracellular domain (NICD) that acts as transcriptional co-activator of the DNA-binding protein CSL. In the absence of signal, a repre...

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Autors principals: Heiko Praxenthaler, Anja C Nagel, Adriana Schulz, Mirjam Zimmermann, Markus Meier, Hannes Schmid, Anette Preiss, Dieter Maier
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2017-05-01
Col·lecció:PLoS Genetics
Accés en línia:http://europepmc.org/articles/PMC5438185?pdf=render
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