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Hairless-binding deficient Suppressor of Hairless alleles reveal Su(H) protein levels are dependent on complex formation with Hairless.

Cell fate choices during metazoan development are driven by the highly conserved Notch signalling pathway. Notch receptor activation results in release of the Notch intracellular domain (NICD) that acts as transcriptional co-activator of the DNA-binding protein CSL. In the absence of signal, a repre...

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Detalhes bibliográficos
Principais autores: Heiko Praxenthaler, Anja C Nagel, Adriana Schulz, Mirjam Zimmermann, Markus Meier, Hannes Schmid, Anette Preiss, Dieter Maier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2017-05-01
Colecção:PLoS Genetics
Acesso em linha:http://europepmc.org/articles/PMC5438185?pdf=render
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