Accumulation of endogenous free radicals is required to induce titan-like cell formation in Cryptococcus neoformans

ABSTRACTCryptococcus neoformans is an encapsulated yeast able to cause disease (mainly meningoencephalitis) among immunosuppressed patients, mostly HIV+. This yeast can form the so-called titan cells in vivo, which are cells of an abnormally larger size due to an increase in both the capsule and the...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Irene García-Barbazán, Alba Torres-Cano, Rocío García-Rodas, Martin Sachse, Daniel Luque, Diego Megías, Oscar Zaragoza
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology 2024-01-01
Σειρά:	mBio
Θέματα:	Cryptococcus neoformans off-patent drug repurposing titan-like cells reactive oxygen species mitochondria
Διαθέσιμο Online:	https://journals.asm.org/doi/10.1128/mbio.02549-23
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