Reduction of β-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease

<p>Abstract</p> <p>Background</p> <p>Aβ deposits represent a neuropathological hallmark of Alzheimer's disease (AD). Both soluble and insoluble Aβ species are considered to be responsible for initiating the pathological cascade that eventually leads to AD. Therefore, the identification of therapeuti...

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Autores principales:	Bachmeier Corbin, Beaulieu-Abdelahad David, Patel Nikunj S, Laporte Vincent, Ganey Nowell J, Paris Daniel, March Amelia, Ait-Ghezala Ghania, Mullan Michael J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2010-03-01
Colección:	Journal of Neuroinflammation
Acceso en línea:	http://www.jneuroinflammation.com/content/7/1/17
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