Código QR (código de barras bidimensional)

Alzheimer’s disease pathological lesions activate the spleen tyrosine kinase

Abstract The pathology of Alzheimer’s disease (AD) is characterized by dystrophic neurites (DNs) surrounding extracellular Aβ-plaques, microgliosis, astrogliosis, intraneuronal tau hyperphosphorylation and aggregation. We have previously shown that inhibition of the spleen tyrosine kinase (Syk) lowe...

ver descrição completa

Na minha lista:
Principais autores: Jonas Elias Schweig, Hailan Yao, David Beaulieu-Abdelahad, Ghania Ait-Ghezala, Benoit Mouzon, Fiona Crawford, Michael Mullan, Daniel Paris
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-09-01
coleção:Acta Neuropathologica Communications
Assuntos:
Alzheimer’s disease
Spleen tyrosine Kinase
Dystrophic neurite
Aβ
sAPPβ
BACE1
Acesso em linha:http://link.springer.com/article/10.1186/s40478-017-0472-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados