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A Fenchone Derivative Effectively Abrogates Joint Damage Following Post-Traumatic Osteoarthritis in Lewis Rats

Background: In a previous report, we have identified the cannabinoid receptor 2 (CB2) agonist HU308 to possess a beneficial effect in preventing age and trauma-induced osteoarthritis (OA) in mice. The effects of HU308 were largely related to the capacity of this compound to induce cartilage anabolis...

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Main Authors: Idan Carmon, Reem Smoum, Eli Farhat, Eli Reich, Leonid Kandel, Zhannah Yekhtin, Ruth Gallily, Raphael Mechoulam, Mona Dvir-Ginzberg
Format: Artigo
Language:Inglês
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
fenchone derivatives
cartilage
osteoarthritis
anabolism
joint structure
DMOAD
Online Access:https://www.mdpi.com/2073-4409/11/24/4084
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