Raf activation is regulated by tyrosine 510 phosphorylation in Drosophila.

The proto-oncoprotein Raf is pivotal for mitogen-activated protein kinase (MAPK) signaling, and its aberrant activation has been implicated in multiple human cancers. However, the precise molecular mechanism of Raf activation, especially for B-Raf, remains unresolved. By genetic and biochemical stud...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Fan Xia, Jinghong Li, Gavin W Hickey, Amy Tsurumi, Kimberly Larson, Dongdong Guo, Shian-Jang Yan, Louis Silver-Morse, Willis X Li
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Public Library of Science (PLoS) 2008-05-01
Цуврал:	PLoS Biology
Онлайн хандалт:	https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.0060128&type=printable
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!