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Proton Nuclear Magnetic Resonance Metabolomics Corroborates Serine Hydroxymethyltransferase as the Primary Target of 2-Aminoacrylate in a <italic toggle="yes">ridA</italic> Mutant of <named-content content-type="genus-species">Salmonella enterica</named-content>

ABSTRACT The reactive intermediate deaminase RidA (EC 3.5.99.10) is conserved across all domains of life and deaminates reactive enamine species. When Salmonella enterica ridA mutants are grown in minimal medium, 2-aminoacrylate (2AA) accumulates, damages several pyridoxal 5′-phosphate (PLP)-depende...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Andrew J. Borchert, Goncalo J. Gouveia, Arthur S. Edison, Diana M. Downs
Hōputu: Artigo
Reo:Inglês
I whakaputaina: American Society for Microbiology 2020-04-01
Rangatū:mSystems
Ngā marau:
Urunga tuihono:https://journals.asm.org/doi/10.1128/mSystems.00843-19
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