Remote Homology Detection Identifies a Eukaryotic RPA DBD-C-like DNA Binding Domain as a Conserved Feature of Archaeal Rpa1-Like Proteins
The eukaryotic single-stranded DNA binding factor replication protein A (RPA) is essential for DNA replication, repair and recombination. RPA is a heterotrimer containing six related OB folds and a winged helix-turn-helix (wH) domain. The OB folds are designated DBD-A through DBD-F, with DBD-A throu...
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| Formato: | Artigo |
| Idioma: | Inglês |
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Frontiers Media S.A.
2021-07-01
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| coleção: | Frontiers in Molecular Biosciences |
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| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fmolb.2021.675229/full |
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