Clonally Expanded Virus-Specific CD8 T Cells Acquire Diverse Transcriptional Phenotypes During Acute, Chronic, and Latent Infections

CD8+ T cells play a crucial role in the control and resolution of viral infections and can adopt a wide range of phenotypes and effector functions depending on the inflammatory context and the duration and extent of antigen exposure. Similarly, viral infections can exert diverse selective pressures...

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Autors principals:	Raphael Kuhn, Ioana Sandu, Andreas Agrafiotis, Kai-Lin Hong, Danielle Shlesinger, Daniel Neimeier, Doron Merkler, Annette Oxenius, Sai T. Reddy, Alexander Yermanos
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-02-01
Col·lecció:	Frontiers in Immunology
Matèries:	T cell single-cell ‘omics’ repertoire viral infection
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.782441/full
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