Quantification of Inter-Sample Differences in T-Cell Receptor Repertoires Using Sequence-Based Information

Inter-sample comparisons of T-cell receptor (TCR) repertoires are crucial for gaining a better understanding of the immunological states determined by different collections of T cells from different donor sites, cell types, and genetic and pathological backgrounds. For quantitative comparison, most...

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Detalhes bibliográficos

Principais autores:	Ryo Yokota, Yuki Kaminaga, Tetsuya J. Kobayashi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2017-11-01
coleção:	Frontiers in Immunology
Assuntos:	T cell TCR repertoire inter-repertoire comparison pairwise sequence alignment sequence dissimilarity manifold learning
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01500/full
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