Organized B cell sites in cartilaginous fishes reveal the evolutionary foundation of germinal centers

Summary: The absence of germinal centers (GCs) in cartilaginous fishes lies at odds with data showing that nurse sharks can produce robust antigen-specific responses and affinity mature their B cell repertoires. To investigate this apparent incongruity, we performed RNA sequencing on single nuclei,...

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Detalles Bibliográficos

Principais autores:	Hanover Matz, Richard S. Taylor, Anthony K. Redmond, Thomas M. Hill, Rose Ruiz Daniels, Mariana Beltran, Neil C. Henderson, Daniel J. Macqueen, Helen Dooley
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2023-07-01
Series:	Cell Reports
Assuntos:	CP: Immunology
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2211124723006757
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