The impact of metabolic reprogramming on tertiary lymphoid structure formation: enhancing cancer immunotherapy

Abstract Background Cancer immunotherapy has achieved unprecedented success in the field of cancer therapy. However, its potential is constrained by a low therapeutic response rate. Main body Tertiary lymphoid structure (TLS) plays a crucial role in antitumor immunity and is associated with a good p...

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Auteurs principaux:	Meng-Jie Zhang, Yan Wen, Zhi-Jun Sun
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2025-04-01
Collection:	BMC Medicine
Sujets:	Tertiary lymphoid structure Metabolic reprogramming Cancer immunotherapy T follicular helper cell Germinal center B cell
Accès en ligne:	https://doi.org/10.1186/s12916-025-04037-7
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