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Mutational spectrum of DNA damage and mismatch repair genes in prostate cancer

Over the past few years, a number of studies have revealed that a significant number of men with prostate cancer had genetic defects in the DNA damage repair gene response and mismatch repair genes. Certain of these modifications, notably gene alterations known as homologous recombination (HRR) gene...

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Principais autores: Fidelis Charles Bugoye, Rispah Torrorey-Sawe, Richard Biegon, Nazima Dharsee, Fidelice M. S. Mafumiko, Kirtika Patel, Simeon K. Mining
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-09-01
Serier:Frontiers in Genetics
Fag:
mutation
DNA damage
prostate cancer
mismatch
repair-deficient
landscape
Online adgang:https://www.frontiersin.org/articles/10.3389/fgene.2023.1231536/full
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