<it>TMPRSS2-ERG </it>-specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling

<p>Abstract</p> <p>Background</p> <p><it>TMPRSS2-ERG </it>gene fusions occur in about 50% of all prostate cancer cases and represent promising markers for molecular subtyping. Although <it>TMPRSS2-ERG </it>fusion seems to be a critical event in prostate cancer, the precise functional role in cancer...

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Detalhes bibliográficos

Principais autores:	Brase Jan C, Johannes Marc, Mannsperger Heiko, Fälth Maria, Metzger Jennifer, Kacprzyk Lukasz A, Andrasiuk Tatjana, Gade Stephan, Meister Michael, Sirma Hüseyin, Sauter Guido, Simon Ronald, Schlomm Thorsten, Beißbarth Tim, Korf Ulrike, Kuner Ruprecht, Sültmann Holger
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2011-12-01
coleção:	BMC Cancer
Assuntos:	Prostate cancer <it>TMPRSS2-ERG</it> Gene expression profiling
Acesso em linha:	http://www.biomedcentral.com/1471-2407/11/507
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