Decreased serpin C1 in extracellular vesicles predicts response to methotrexate treatment in patients with pulmonary sarcoidosis

Abstract Background Sarcoidosis is a systemic granulomatous disease of unknown etiology primarily affecting the lungs. Treatment is needed when disease symptoms worsen and organ function deteriorates. In pulmonary sarcoidosis, prednisone and methotrexate (MTX) are the most common anti-inflammatory t...

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Bibliografische gegevens

Hoofdauteurs:	Raisa Kraaijvanger, Montse Janssen Bonás, Jan C. Grutters, Ioanna Paspali, Marcel Veltkamp, Dominique P. V. de Kleijn, Coline H. M. van Moorsel
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2024-04-01
Reeks:	Respiratory Research
Onderwerpen:	Extracellular vesicles Sarcoidosis Biomarkers Therapy
Online toegang:	https://doi.org/10.1186/s12931-024-02809-y
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