The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson’s disease

Interferon regulatory factor 7 plays a crucial role in the innate immune response. However, whether interferon regulatory factor 7-mediated signaling contributes to Parkinson’s disease remains unknown. Here we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl...

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Principais autores:	Shengyang Zhou, Ting Li, Wei Zhang, Jian Wu, Hui Hong, Wei Quan, Xinyu Qiao, Chun Cui, Chenmeng Qiao, Weijiang Zhao, Yanqin Shen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wolters Kluwer Medknow Publications 2025-08-01
coleção:	Neural Regeneration Research
Assuntos:	cyclic guanosine monophosphate adenosine monophosphate synthase h151 interferon regulatory factor 7 m1 phenotype neurodegenerative disease neuroinflammation parkinson’s disease ru521 sting type i interferon
Acesso em linha:	https://journals.lww.com/10.4103/NRR.NRR-D-23-01684
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