Código QR (código de barras bidimensional)

Exploration of precision coregulator TR-FRET identifies diverse signatures for LXR ligands relevant to discovery of nonlipogenic ABCA1 inducers

APOE4, the major genetic risk factor for Alzheimer’s disease (AD), and ATP-binding cassette-A1 (ABCA1), required for lipidation of APOE are gene products of the liver X receptor (LXR) receptor. LXR agonists have been validated in animal models as therapeutics for AD, atherosclerosis, and many other...

Fuld beskrivelse

Na minha lista:
Principais autores: Megan S Laham, Martha S Ackerman-Berrier, Fahmida Alam, Sarah Turner, Ganga Reddy Velma, Christopher Penton, Soumya Reddy Musku, Manan Rana, Senthilkumar Thulasingam, Anandhan Annadurai, Maha Ibrahim Sulaiman, Nina Ma, Gregory RJ Thatcher
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2026-06-01
Serier:eLife
Fag:
liver X receptor
LXR
ATP-binding cassette-A1
coregulator selectivity
lipogenesis
Online adgang:https://elifesciences.org/articles/109146
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker