Synthetic Route to Glycosyl β-1C-(phosphino)-phosphonates as Unprecedented Stable Glycosyl Diphosphate Analogs and Their Preliminary Biological Evaluation

The synthesis of glycosyl-β-1<i>C</i>-(phosphino)-phosphonates is a challenge since it has not yet been described. In this paper, we report an innovative synthetic method for their preparation from Glc-, Man-, and Glc<i>N</i>Ac- lactone derivatives. The proposed original strategy involves the additi...

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Bibliografiske detaljer

Principais autores:	Michaël Bosco, Su-Jin Paik, Patricia Busca, Stuart E. H. Moore, Christine Gravier-Pelletier
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2020-10-01
Serier:	Molecules
Fag:	<i>C</i>-glycoside diphosphate analogs phosphinophosphonate alkaline diphosphatase glycochemistry
Online adgang:	https://www.mdpi.com/1420-3049/25/21/4969
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