Synthesis and Preliminary Biological Evaluations of 5′-Substituted Derivatives of Uridine as Glycosyltransferase Inhibitors

New derivatives of uridine which contain a b-ketoenol motif were synthesized, characterized and biologically tested. Synthesized compounds 1–4 showed no activity against bovine milk β-1,4-galactosyltransferase I at concentrations up to 2.0 mM and were not active against Candida albicans and Aspergil...

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Detalles Bibliográficos

Principais autores:	Ilona Wandzik, Wiesław Szeja, Urszula Nawrot, Tadeusz Bieg, Katarzyna Kral, Jadwiga Paszkowska
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2013-07-01
Series:	Molecules
Assuntos:	uridine glycosyltransferase inhibitors antifungal activity
Acceso en liña:	http://www.mdpi.com/1420-3049/18/7/8018
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