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Quantitative evaluation of cellular internalization of polymeric nanoparticles within laryngeal cancer cells and immune cells for enhanced drug delivery

Abstract Clinical translation of poly (lactic-co-glycolic acid) (PLGA)-based nanomedicine is limited, partly because of the poor delivery efficiency resulting from non-specific phagocytosis by phagocytes. Understanding the nanoparticle interplay between cancer cells and immune cells remains largely...

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Principais autores: Li-Juan Ma, Ruichao Niu, Xi Wu, Jun Wu, En Zhou, Xu-Ping Xiao, Jie Chen
Formato: Artigo
Idioma:Inglês
Publicado: SpringerOpen 2021-03-01
Series:Nanoscale Research Letters
Assuntos:
Cellular uptake
Co-culture
Cytotoxicity
Laryngeal cancer
Polymeric particles
Cell fusion
Acceso en liña:https://doi.org/10.1186/s11671-021-03498-y
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