Bovine Pancreatic RNase A: An Insight into the Mechanism of Antitumor Activity In Vitro and In Vivo

In this investigation, we extensively studied the mechanism of antitumor activity of bovine pancreatic RNase A. Using confocal microscopy, we show that after RNase A penetration into HeLa and B16 cells, a part of the enzyme remains unbound with the ribonuclease inhibitor (RI), resulting in the decre...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Islam Saber Ead Mohamed, Aleksandra V. Sen’kova, Oleg V. Markov, Andrey V. Markov, Innokenty A. Savin, Marina A. Zenkova, Nadezhda L. Mironova
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-05-01
Edice:	Pharmaceutics
Témata:	RNase A ribonuclease inhibitor antitumor activity intracellular localization Ku70/Ku80 miRNA
On-line přístup:	https://www.mdpi.com/1999-4923/14/6/1173
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!