Macrophage-mediated tumor-targeted delivery of engineered Salmonella typhimurium VNP20009 in anti-PD1 therapy against melanoma

Bacterial antitumor therapy has great application potential given its unique characteristics, including genetic manipulation, tumor targeting specificity and immune system modulation. However, the nonnegligible side effects and limited efficacy of clinical treatment limit their biomedical applicatio...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Leyang Wu, Lin Li, Shufeng Li, Lina Liu, Wenjie Xin, Chenyang Li, Xingpeng Yin, Xuebo Xu, Feifei Bao, Zichun Hua
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2022-10-01
Цуврал:	Acta Pharmaceutica Sinica B
Нөхцлүүд:	Macrophage Salmonella typhimurium VNP20009 Anti-PD1 nanobody Tumor-targeted delivery Immune activation
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S221138352200212X
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!