The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate.
Homeostasis of most adult tissues is maintained by balancing stem cell self-renewal and differentiation, but whether post-transcriptional mechanisms can regulate this process is unknown. Here, we identify that an RNA methyltransferase (Misu/Nsun2) is required to balance stem cell self-renewal and di...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2011-12-01
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| Col·lecció: | PLoS Genetics |
| Accés en línia: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002403&type=printable |
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