Shape-induced terminal differentiation of human epidermal stem cells requires p38 and is regulated by histone acetylation.

Engineered model substrates are powerful tools for examining interactions between stem cells and their microenvironment. Using this approach, we have previously shown that restricted cell adhesion promotes terminal differentiation of human epidermal stem cells via activation of serum response factor...

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Detalles Bibliográficos

Autores principales:	John T Connelly, Ajay Mishra, Julien E Gautrot, Fiona M Watt
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2011-01-01
Colección:	PLoS ONE
Acceso en línea:	http://europepmc.org/articles/PMC3206954?pdf=render
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