Tubular aryl hydratocarbon receptor upregulates EZH2 to promote cellular senescence in cisplatin-induced acute kidney injury

Abstract Acute kidney injury (AKI) is one of the serious clinical syndromes with high morbidity and mortality. Despite substantial progress in understanding the mechanism of AKI, no effective drug is available for treatment or prevention. In this study, we identified that a ligand-activated transcri...

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Detalhes bibliográficos

Principais autores:	Li Wen, Qian Ren, Fan Guo, Xiaoyan Du, Hongliu Yang, Ping Fu, Liang Ma
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2023-01-01
coleção:	Cell Death and Disease
Assuntos:	Acute kidney injury Aryl hydrocarbon receptor Enhancer of zeste homolog 2 Cellular senescence.
Acesso em linha:	https://doi.org/10.1038/s41419-022-05492-3
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