Delayed Neurologic Response to Dabrafenib and Trametinib in the Case of Mixed Histiocytosis (LCH/ECD): Case Report and Literature Review

<b>Background and Clinical Significance</b>: Histiocytosis encompasses Langerhans cell histiocytosis (LCH) and non-LCH, such as Erdheim–Chester disease (ECD). ECD or a mixed type of histiocytosis (LCH/ECD) may initially involve the central nervous system (CNS), resulting in a delayed diagnosis. More...

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Auteurs principaux:	Shinsaku Imashuku, Miyako Kobayashi, Takashi Miyoshi, Naoyuki Anzai
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2026-01-01
Collection:	Reports
Sujets:	Langerhans cell histiocytosis Erdheim–Chester disease mixed histiocytosis dabrafenib trametinib neurological symptoms
Accès en ligne:	https://www.mdpi.com/2571-841X/9/1/18
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