Microenvironmental pH-Modulated Dissolution of Albendazole Layered on Tartaric Acid Starter Pellet Cores

<b>Background/Objectives</b>: To improve the therapeutic efficacy of albendazole (ABZ) for ileocolonic diseases, its low solubility at higher pH levels should be enhanced. Organic acids have been widely used as pH modifiers to improve the solubility of weakly basic drugs. To achieve an a...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kristina Vlahovic, Miléna Lengyel, Christian Fleck, Nikolett Kállai-Szabó, Emese Balogh, András József Laki, István Antal
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2025-08-01
Saila:Pharmaceutics
Gaiak:
multiparticulate
layered pellet
modified release
solubility enhancement
albendazole
inert core
Sarrera elektronikoa:https://www.mdpi.com/1999-4923/17/9/1133
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