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MUPS Tableting—Comparison between Crospovidone and Microcrystalline Cellulose Core Pellets

Multi-unit pellet system (MUPS) tablets were fabricated by compacting drug-loaded pellets of either crospovidone or microcrystalline cellulose core. These pellets were produced by extrusion-spheronization and coated with ethylcellulose (EC) for a sustained drug release function. Coat damage due to t...

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Principais autores: Daniel Robin Thio, Paul Wan Sia Heng, Lai Wah Chan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-12-01
Serier:Pharmaceutics
Fag:
MUPS tablet
pellet core
spheronization aid
ethylcellulose
pellet coat damage
crospovidone
Online adgang:https://www.mdpi.com/1999-4923/14/12/2812
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