Tracing the tissue origin of cell-free DNA through open chromatin footprint
Abstract Plasma cell-free DNA (cfDNA) is a promising biomarker for liquid biopsy, essential for diagnosing and monitoring diseases. Current methods for estimating tissue contributions primarily rely on methylation markers, which can damage cfDNA, limiting clinical use. While research shows cfDNA cov...
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| Principais autores: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2025-11-01
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| Serier: | Communications Biology |
| Online adgang: | https://doi.org/10.1038/s42003-025-09232-z |
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