Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastoma
Abstract The majority of high-risk neuroblastomas can be divided into three distinct molecular subgroups defined by the presence of MYCN amplification, upstream TERT rearrangements or alternative lengthening of telomeres (ALT). The common defining feature of all three subgroups is altered telomere m...
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| Principais autores: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BMC
2020-05-01
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| 叢編: | Journal of Experimental & Clinical Cancer Research |
| 主題: | |
| 在線閱讀: | http://link.springer.com/article/10.1186/s13046-020-01582-2 |
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