Charge reduction and thermodynamic stabilization of substrate RNAs inhibit RNA editing.

African trypanosomes cause a parasitic disease known as sleeping sickness. Mitochondrial transcript maturation in these organisms requires a RNA editing reaction that is characterized by the insertion and deletion of U-nucleotides into otherwise non-functional mRNAs. Editing represents an ideal targ...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	W-Matthias Leeder, Andreas J Reuss, Michael Brecht, Katja Kratz, Josef Wachtveitl, H Ulrich Göringer
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Public Library of Science (PLoS) 2015-01-01
Цуврал:	PLoS ONE
Онлайн хандалт:	https://doi.org/10.1371/journal.pone.0118940
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!