NR4A1 deletion promotes pro-angiogenic polarization of macrophages derived from classical monocytes in a mouse model of neovascular age-related macular degeneration

Abstract Background Neovascular age-related macular degeneration causes vision loss from destructive angiogenesis, termed choroidal neovascularization (CNV). Cx3cr1 −/− mice display alterations in non-classical monocytes and microglia with increased CNV size, suggesting that non-classical monocytes...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Steven Droho, Andrew P. Voigt, Jacob K. Sterling, Amrita Rajesh, Kyle S. Chan, Carla M. Cuda, Harris Perlman, Jeremy A. Lavine
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-10-01
coleção:	Journal of Neuroinflammation
Assuntos:	Angiogenesis Choroidal neovascularization Macrophage Monocyte Non-classical monocytes Neovascular age-related macular degeneration
Acesso em linha:	https://doi.org/10.1186/s12974-023-02928-1
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!