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Formyl peptide receptor 1 suppresses gastric cancer angiogenesis and growth by exploiting inflammation resolution pathways

Chronic inflammation can result from inadequate engagement of resolution mechanisms, mainly accomplished by specialized pro-resolving mediators (SPMs) arising from the metabolic activity of lipoxygenases (ALOX5/15) on ω-6 or ω-3 essential polyunsaturated fatty acids (PUFA). We previously demonstrate...

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Principais autores: Nella Prevete, Federica Liotti, Anna Illiano, Angela Amoresano, Piero Pucci, Amato de Paulis, Rosa Marina Melillo
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2017-04-01
Serier:OncoImmunology
Fag:
angiogenesis
formyl peptide receptors
gastric cancer
lipoxin b4
pro-resolving pathways
resolvin d1
Online adgang:http://dx.doi.org/10.1080/2162402X.2017.1293213
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