Indole-Based Tubulin Inhibitors: Binding Modes and SARs Investigations
Tubulin inhibitors can interfere with normal cell mitosis and inhibit cell proliferation through interfering with the normal structure and function of microtubules, forming spindle filaments. Indole, as a privileged pharmacological skeleton, has been widely used in anti-cancer inhibitors. A variety...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI AG
2022-02-01
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| Collection: | Molecules |
| Sujets: | |
| Accès en ligne: | https://www.mdpi.com/1420-3049/27/5/1587 |
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