Proteome-wide Mendelian randomization and colocalization analysis uncovers druggable targets for lung cancer across multiple phenotypes and complications

Abstract Background Lung cancer remains a leading cause of cancer-related mortality, necessitating novel therapeutic targets. The plasma proteome represents a key source for such targets. Methods Proteome-wide Mendelian randomization (MR) and colocalization analyses were conducted to assess the caus...

Szczegółowa specyfikacja

Opis bibliograficzny

Główni autorzy:	Yunpeng Chen, Xiaohong Dai, Peng Zhang, Lijuan Yao, Qing Wang, Zhihong Qin, Tianmin Gao, Junguo Zhang
Format:	Artigo
Język:	Inglês
Wydane:	Springer 2025-11-01
Seria:	Discover Oncology
Hasła przedmiotowe:	Mendelian randomization Lung cancer Therapeutic targets Proteome-wide analysis
Dostęp online:	https://doi.org/10.1007/s12672-025-03910-4
Etykiety:	Dodaj etykietę Nie ma etykietki, Dołącz pierwszą etykiete!