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Is natural (6S)-5-methyltetrahydrofolic acid as effective as synthetic folic acid in increasing serum and red blood cell folate concentrations during pregnancy? A proof-of-concept pilot study

Abstract Background North American health authorities recommend 0.4 mg/day folic acid before conception and throughout pregnancy to reduce the risk of neural tube defects. Folic acid is a synthetic form of folate that must be reduced by dihydrofolate reductase and then further metabolized. Recent ev...

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Bibliografische Detailangaben
Hauptverfasser: Kelsey M. Cochrane, Chantal Mayer, Angela M. Devlin, Rajavel Elango, Jennifer A. Hutcheon, Crystal D. Karakochuk
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2020-05-01
Schriftenreihe:Trials
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Online-Zugang:http://link.springer.com/article/10.1186/s13063-020-04320-3
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