Implications of Advances in Studies of O6-Methylguanine-DNA- Methyltransferase for Tumor Prognosis and Treatment
O6-methylguanine-DNA-methyltransferase (MGMT) is a DNA repair enzyme, which reverses the alkylation of guanine O6 through directtransfer of the methyl group, maintains the gene stability and avoids tumor occurrence. Studies have shown that MGMT gene methylation, polymorphism and protein expression a...
محفوظ في:
| المؤلفون الرئيسيون: | , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
IMR Press
2023-09-01
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| سلاسل: | Frontiers in Bioscience-Landmark |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://www.imrpress.com/journal/FBL/28/9/10.31083/j.fbl2809197 |
| الوسوم: |
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