Cognitive function correlates with gastric alpha-synuclein seeding activity in early Parkinson’s disease

Abstract Alpha-synuclein (AS) accumulation is more frequently detected in the stomach than in the colon of patients with Parkinson’s disease (PD), suggesting its potential as a pathologic biomarker. This study is to evaluate the diagnostic performance of real-time quaking-induced conversion assay on...

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Detalhes bibliográficos

Principais autores:	Chaewon Shin, Jong Pil Im, Jung-Youn Han, Bora Jin, Kyung Ah Woo, Seungmin Lee, HoYoung Jeon, Jae Young Joo, Hee Jin Chang, Jung Hwan Shin, Han-Joon Kim, Jong-Min Kim, Young Pyo Choi, Beomseok Jeon
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-11-01
coleção:	npj Parkinson's Disease
Acesso em linha:	https://doi.org/10.1038/s41531-025-01152-3
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