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RT-QuIC and Related Assays for Detecting and Quantifying Prion-like Pathological Seeds of α-Synuclein

Various disease-associated forms or strains of α-synuclein (αSyn<sup>D</sup>) can spread and accumulate in a prion-like fashion during synucleinopathies such as Parkinson’s disease (PD), Lewy body dementia (DLB), and multiple system atrophy (MSA). This capacity for self-propagation has enabled the d...

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Hlavní autoři: Ankit Srivastava, Parvez Alam, Byron Caughey
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2022-04-01
Edice:Biomolecules
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On-line přístup:https://www.mdpi.com/2218-273X/12/4/576
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