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Blood-based epigenome-wide analyses of cognitive abilities

Abstract Background Blood-based markers of cognitive functioning might provide an accessible way to track neurodegeneration years prior to clinical manifestation of cognitive impairment and dementia. Results Using blood-based epigenome-wide analyses of general cognitive function, we show that indivi...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Daniel L. McCartney, Robert F. Hillary, Eleanor L. S. Conole, Daniel Trejo Banos, Danni A. Gadd, Rosie M. Walker, Cliff Nangle, Robin Flaig, Archie Campbell, Alison D. Murray, Susana Muñoz Maniega, María del C. Valdés-Hernández, Mathew A. Harris, Mark E. Bastin, Joanna M. Wardlaw, Sarah E. Harris, David J. Porteous, Elliot M. Tucker-Drob, Andrew M. McIntosh, Kathryn L. Evans, Ian J. Deary, Simon R. Cox, Matthew R. Robinson, Riccardo E. Marioni
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2022-01-01
Schriftenreihe:Genome Biology
Schlagworte:
DNA methylation
EWAS
Cognitive ability
Prediction
Epidemiology
Online-Zugang:https://doi.org/10.1186/s13059-021-02596-5
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