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Fucosyltransferase 4 shapes oncogenic glycoproteome to drive metastasis of lung adenocarcinoma

Background: Aberrant fucosylation plays a critical role in lung cancer progression. Nevertheless, the key fucosyltransferase with prognostic significance in lung cancer patients, the enzyme's intracellular targets, and complex molecular mechanisms underlying lung cancer metastasis remain incompletel...

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Hoofdauteurs: Hsuan-Hsuan Lu, Shu-Yung Lin, Rueyhung Roc Weng, Yi-Hsiu Juan, Yen-Wei Chen, Hsin-Han Hou, Zheng-Ci Hung, Giovanni Audrey Oswita, Yi-Jhen Huang, Shih-Yun Guu, Kay-Hooi Khoo, Jin-Yuan Shih, Chong-Jen Yu, Hsing-Chen Tsai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020-07-01
Reeks:EBioMedicine
Onderwerpen:
Fucosyltransferase
Lung cancer
Cancer metastasis
Terminal fucosylation
Glycoproteomics
Online toegang:http://www.sciencedirect.com/science/article/pii/S2352396420302218
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