Fucosylated Antigens in Cancer: An Alliance toward Tumor Progression, Metastasis, and Resistance to Chemotherapy

Aberrant glycosylation of tumor cells is recognized as a universal hallmark of cancer pathogenesis. Overexpression of fucosylated epitopes, such as type I (H1, Lewisa, Lewisb, and sialyl Lewisa) and type II (H2, Lewisx, Lewisy, and sialyl Lewisx) Lewis antigens, frequently occurs on the cancer cell...

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Detalhes bibliográficos

Principais autores:	Athanasios Blanas, Neha M. Sahasrabudhe, Ernesto Rodríguez, Yvette van Kooyk, Sandra J. van Vliet
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-02-01
coleção:	Frontiers in Oncology
Assuntos:	cancer glycosylation fucosylation fucosyltransferases Lewis antigens
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fonc.2018.00039/full
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