Effect of knee joint loading on chondrocyte mechano-vulnerability and severity of post-traumatic osteoarthritis induced by ACL-injury in mice

Objective: The objective of this study is to understand the role of altered in vivo mechanical environments in knee joints post anterior cruciate ligament (ACL)-injury in chondrocyte vulnerability against mechanical stimuli and in the progression of post-traumatic osteoarthritis (PT-OA). Methods: Di...

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Bibliographic Details

Main Authors:	Alexander Kotelsky, Anissa Elahi, Can Nejat Yigit, Ashley Proctor, Sandeep Mannava, Christoph Pröschel, Whasil Lee
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2022-03-01
Series:	Osteoarthritis and Cartilage Open
Subjects:	Post-traumatic osteoarthritis (PT-OA) Anterior cruciate ligament (ACL)-injury Chondrocyte death Extracellular matrix (ECM) Gait analysis
Online Access:	http://www.sciencedirect.com/science/article/pii/S266591312100090X
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