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PIEZO1 is downregulated in glenohumeral chondrocytes in early cuff tear arthropathy following a massive rotator cuff tear in a mouse model

Introduction: A massive rotator cuff tear (RCT) leads to glenohumeral joint destabilization and characteristic degenerative changes, termed cuff tear arthropathy (CTA). Understanding the response of articular cartilage to a massive RCT will elucidate opportunities to promote homeostasis following re...

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Principais autores: Devon E. Anderson, Katherine G. Broun, Paromita Kundu, Xingyu Jing, Xiang Tang, Christopher Lu, Alexander Kotelsky, Sandeep Mannava, Whasil Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-09-01
coleção:Frontiers in Bioengineering and Biotechnology
Assuntos:
articular cartilage
chondrocyte
rotator cuff tear (RCT)
cuff tear arthropathy (CTA)
PIEZO1 channel
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1244975/full
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