A porphodimethene chemical inhibitor of uroporphyrinogen decarboxylase.

Uroporphyrinogen decarboxylase (UROD) catalyzes the conversion of uroporphyrinogen to coproporphyrinogen during heme biosynthesis. This enzyme was recently identified as a potential anticancer target; its inhibition leads to an increase in reactive oxygen species, likely mediated by the Fenton react...

Descripció completa

Dades bibliogràfiques

Autors principals:	Kenneth W Yip, Zhan Zhang, Noriko Sakemura-Nakatsugawa, Jui-Wen Huang, Nhu Mai Vu, Yi-Kun Chiang, Chih-Lung Lin, Jennifer Y Y Kwan, Shijun Yue, Yulia Jitkova, Terence To, Payam Zahedi, Emil F Pai, Aaron D Schimmer, Jonathan F Lovell, Jonathan L Sessler, Fei-Fei Liu
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2014-01-01
Col·lecció:	PLoS ONE
Accés en línia:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089889&type=printable
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!