Effects of perioperative dexmedetomidine on renal vascular function and renovascular histopathology in ovine cardiopulmonary bypass

Abstract Background Cardiopulmonary bypass (CPB) is integral to the conduct of cardiac surgery but is associated with postoperative acute kidney injury (AKI). Dexmedetomidine, an α₂-adrenoceptor agonist with anti-inflammatory and sympatholytic properties, has putative renoprotective effects. In a re...

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Principais autores:	Ashenafi H. Betrie, Alemayehu H. Jufar, Roger G. Evans, Andrew D. Cochrane, Bruno Marino, Ian Birchall, Sally G. Hood, Peter R. McCall, Scott Ayton, Lachlan F. Miles, Clive N. May, Yugeesh R. Lankadeva
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	SpringerOpen 2025-12-01
סדרה:	Intensive Care Medicine Experimental
נושאים:	Cardiopulmonary bypass CPB Dexmedetomidine Acute kidney injury Renal interlobar arteries Vasoconstriction
גישה מקוונת:	https://doi.org/10.1186/s40635-025-00836-7
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!