CCN Family Proteins in Cancer: Insight Into Their Structures and Coordination Role in Tumor Microenvironment

The crosstalk between tumor cells and the tumor microenvironment (TME), triggers a variety of critical signaling pathways and promotes the malignant progression of cancer. The success rate of cancer therapy through targeting single molecule of this crosstalk may be extremely low, whereas co-targetin...

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Autori principali:	Qingan Jia, Binghui Xu, Yaoyao Zhang, Arshad Ali, Xia Liao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2021-03-01
Serie:	Frontiers in Genetics
Soggetti:	CCN proteins isoforms targeted therapy tumor microenvironment pan-cancer
Accesso online:	https://www.frontiersin.org/articles/10.3389/fgene.2021.649387/full
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