CCN Family Proteins in Cancer: Insight Into Their Structures and Coordination Role in Tumor Microenvironment

The crosstalk between tumor cells and the tumor microenvironment (TME), triggers a variety of critical signaling pathways and promotes the malignant progression of cancer. The success rate of cancer therapy through targeting single molecule of this crosstalk may be extremely low, whereas co-targetin...

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Bibliografische Detailangaben

Hauptverfasser:	Qingan Jia, Binghui Xu, Yaoyao Zhang, Arshad Ali, Xia Liao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-03-01
Schriftenreihe:	Frontiers in Genetics
Schlagworte:	CCN proteins isoforms targeted therapy tumor microenvironment pan-cancer
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fgene.2021.649387/full
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