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Canagliflozin impairs blood reperfusion of ischaemic lower limb partially by inhibiting the retention and paracrine function of bone marrow derived mesenchymal stem cells

Background: Canagliflozin (CANA) administration increases the risk of lower limb amputation in the clinic. The present study aimed to investigate whether and how CANA interferes with the intracellular physiological processes of bone marrow derived mesenchymal stem cells (BM-MSCs) and its contributio...

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Principais autores: Yinuo Lin, Jinliang Nan, Jian Shen, Xinhuang Lv, Xiao Chen, Xingmei Lu, Chi Zhang, Pingping Xiang, Zhiting Wang, Zhengzheng Li
格式: Artigo
語言:Inglês
出版: Elsevier 2020-02-01
叢編:EBioMedicine
在線閱讀:http://www.sciencedirect.com/science/article/pii/S2352396420300128
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